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- 品牌：MedKoo
- 產(chǎn)地：美國
- 貨號：561256
- cas：163126-81-6
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國 |
| 品牌 | MedKoo |
| 貨號 | 561256 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 10.0mg; 25.0mg; 100.0mg; |
| CAS編號 | 163126-81-6 |
| 純度 | >98%% |
| 是否進口 | 是 |
Description: Sepin-1 is a noncompetitive inhibitor of separase. Sepin-1 inhibits separase enzymatic activity with a half maximal inhibitory concentration (IC50) of 14.8 μM. Sepin-1 can inhibit the growth of human cancer cell lines and breast cancer xenograft tumors in mice by inhibiting cell proliferation and inducing apoptosis.
Synonym: Sepin-1; Sepin 1; Sepin1
IUPAC/Chemical Name: 2,2-Dimethyl-5-nitro-2H-benzimidazole-1,3-dioxide
InChi Key: YLVSVJDCTDBERH-UHFFFAOYSA-N
InChi Code: InChI=1S/C9H9N3O4/c1-9(2)10(13)7-4-3-6(12(15)16)5-8(7)11(9)14/h3-5H,1-2H3
SMILES Code: [O-][N+]1=C2C(C=C([N+]([O-])=O)C=C2)=[N+]([O-])C1(C)C
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
