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- 品牌：MedKoo
- 產(chǎn)地：美國
- 貨號：329838
- cas：84-26-4
- 發(fā)布日期： 2022-07-20
- 更新日期： 2024-08-12
| 產(chǎn)地 | 美國 |
| 品牌 | MedKoo |
| 貨號 | 329838 |
| 用途 | This product is for research use only, not for human or veterinary use. |
| 包裝規(guī)格 | 200.0mg; 500.0mg; 1.0g; |
| CAS編號 | 84-26-4 |
| 純度 | >98%% |
| 是否進(jìn)口 | 是 |
Description: Rutaecarpine, also known as NSC 258317, is a quinazolinone alkaloid originally isolated from E. rutaecarpa that has diverse biological activities. Rutaecarpine prevented dysfunction of endothelial gap junction induced by Ox-LDL via activation of TRPV1. Rutaecarpine inhibits angiotensin II-induced proliferation in rat vascular smooth muscle cells. Rutaecarpine ameliorates hyperlipidemia and hyperglycemia in fat-fed, streptozotocin-treated rats via regulating the IRS-1/PI3K/Akt and AMPK/ACC2 signaling pathways.
Synonym: Rutaecarpine; NSC 258317; NSC-258317; NSC258317.
IUPAC/Chemical Name: 8,13-dihydro-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one
InChi Key: ACVGWSKVRYFWRP-UHFFFAOYSA-N
InChi Code: InChI=1S/C18H13N3O/c22-18-13-6-2-4-8-15(13)20-17-16-12(9-10-21(17)18)11-5-1-3-7-14(11)19-16/h1-8,19H,9-10H2
SMILES Code: O=C1N2C(C(NC3=C4C=CC=C3)=C4CC2)=NC5=C1C=CC=C5
Appearance: Solid powder
Purity: >98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility: Soluble in DMSO
Shelf Life: >2 years if stored properly
Drug Formulation: This drug may be formulated in DMSO
Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code: 2934.99.9001
